Browse Paid Clinical Studies

Real studies from top pharmaceutical companies enrolling participants right now. Free to apply — get paid for your time.

Featured
💻

Streaming Habits Research Panel

User Interviews

Tell researchers how you discover and watch streaming content. One 45-minute online interview via video call.

Paid Research
Online Focus Group
online
$100–$175
1 week
Online / Remote
Featured
💻

Online Consumer Snack Preferences Study

Focus Forward

Share your opinions about new snack flavors in a 60-minute Zoom focus group. Open to adults nationwide who shop for groceries weekly.

Paid Research
Online Focus Group
online
$75–$150
1 week
Online / Remote
💻

Smart Home Device Diary Study

QualSights

Tell researchers how you actually use smart speakers, doorbells, and thermostats. 7 short video diary entries.

Paid Research
Online Focus Group
online
$175–$300
2 weeks
Online / Remote
💻

Remote Workers Productivity Survey Series

dscout

Complete short daily diary entries via mobile app for one week about your work-from-home routine.

Paid Research
Online Focus Group
online
$150–$300
2 weeks
Online / Remote
💻

Pet Owner Online Diary Study

Discuss.io

Document your pet's daily routine via a mobile app for 10 days. Open to dog and cat owners nationwide.

Paid Research
Online Focus Group
online
$150–$275
2 weeks
Online / Remote
💻

Financial Wellness Survey Panel

L.E.K. Consulting

Share your views on saving, budgeting, and investing apps in one 60-minute online group discussion.

Paid Research
Online Focus Group
online
$125–$250
1 week
Online / Remote
💻

Online Skincare Product Testing

Home Tester Club

Receive a free skincare product to try at home for 4 weeks, then complete short surveys about your experience.

Paid Research
Online Focus Group
online
$100–$250
4 weeks
Online / Remote
💻

Sustainable Fashion Online Focus Group

FocusGroup.com

Discuss eco-friendly clothing brands and shopping habits in a 90-minute moderated online session.

Paid Research
Online Focus Group
online
$125–$225
1 week
Online / Remote
💻

Online Fitness App Usability Test

Maze

Try a new workout app for one week and complete short feedback surveys after each session.

Paid Research
Online Focus Group
online
$100–$200
1 week
Online / Remote
💻

Mobile Banking App Usability Study

Respondent.io

Walk through a banking app prototype with a researcher over screen-share. Provide candid feedback on what works and what doesn't.

Paid Research
Online Focus Group
online
$125–$200
1 week
Online / Remote
💻

Parents of Toddlers Online Focus Group

Schlesinger Group

Discuss parenting products, snacks, and routines with other parents in a moderated online group session.

Paid Research
Online Focus Group
online
$100–$200
1 week
Online / Remote
💻

Telehealth Patient Experience Panel

Field Agent

Share your recent telehealth visit experience in a 45-minute online interview. No medical info required.

Paid Research
Online Focus Group
online
$100–$200
1 week
Online / Remote
💻

AI Chatbot Feedback Panel

Prolific

Try a new AI assistant and rate responses across 5 short remote sessions. Fully online, work at your own pace.

Paid Research
Online Focus Group
online
$80–$180
2 weeks
Online / Remote
💻

Coffee Drinker Online Taste Panel

InCrowd

Receive a coffee sampler kit at home, brew it your way, and complete a short online survey.

Paid Research
Online Focus Group
online
$100–$175
2 weeks
Online / Remote
💻

Plant-Based Eating Habits Study

Nielsen Consumer Insights

Share your views on plant-based foods in one 90-minute virtual focus group with other curious eaters.

Paid Research
Online Focus Group
online
$125–$175
1 week
Online / Remote
💻

Travel Booking Behavior Interview

Voxpopme

Share your last trip planning experience in a 30-minute video interview. Fully remote.

Paid Research
Online Focus Group
online
$75–$150
1 week
Online / Remote
💻

Online Gamers Research Interview

Recollective

Tell game studios what you love (and hate) about new releases. One-on-one Zoom interview, 60 minutes.

Paid Research
Online Focus Group
online
$100–$150
1 week
Online / Remote
💻

Online Shopping Cart Abandonment Study

UserTesting

Record yourself shopping on a retailer's website for 30 minutes and explain your decisions out loud.

Paid Research
Online Focus Group
online
$75–$125
1 week
Online / Remote
Featured
⚖️

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and T…

Novo Nordisk A/S

The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and type 2 diabetes. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (treatment that has no active medicine in it). Which treatment participants get is decided by chance.

Phase 3
Weight Loss
in-person
$500–$2,500
3 months
Nationwide
Featured
💉

Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic K…

Regeneron Pharmaceuticals

This study is researching experimental drugs called ALN-ANG3 and evinacumab (called "study drugs"). The study is focused on participants who have diabetic kidney disease. The aim of the study is to see how safe and effective the study drugs are. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood at different times

Phase 2
Diabetes
in-person
$500–$2,500
3 months
Nationwide
Featured
🧠

Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors

The University of Texas Health Science Center, Houston

The overall objective of the project is to determine the effectiveness of tele-delivered behavioral activation (BA) by trained lay counselors (Tele-BA-S) to prevent Post-stroke depression (PSD) in low-income, older stroke survivors with subthreshold depression (SD).

Observational
Mental Health
in-person
$500–$2,500
3 months
Texas
Featured
🧴

A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and Hig…

Eli Lilly and Company

The purpose of this study is to measure how well taking lebrikizumab alone works for participants with fewer places on the body with eczema (atopic dermatitis), but these places may be very itchy. Participation in this study will last up to approximately 38 weeks (9 and a half months) including 24 weeks (6 months) of treatment.

Phase 4
Dermatology
in-person
$500–$2,500
3 months
Nationwide
Featured
🛡️

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmissio…

Hoffmann-La Roche

This study consists of two parts: Part A Surveillance and Part B Transmission. The main purpose of Part A is to evaluate the prevalence of pre-dose and treatment-emergent amino acid substitutions in pediatric participants' susceptibility \<12 years with influenza treated with baloxavir marboxil. Part B will include a subset of Part A participants who have household contacts (HHCs) recruited to the study. Part B will evaluate the incidence of onward influenza transmission from pediatric index…

Phase 3
Vaccine
in-person
$500–$2,500
3 months
Nationwide
Featured
❤️

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Hav…

Pfizer

The purpose of this study is to learn about the long-term safety, tolerability and effects of the study medicine (PF-07868489) for the possible treatment of PAH. PAH is a condition in which there is high blood pressure in the arteries that carry blood from the heart to the lungs. This high pressure makes it harder for the heart to pump blood through those lungs, potentially damaging the right side of the heart. This is an open-label study. Which means that both the healthcare providers and th…

Phase 2
Cardiology
in-person
$500–$2,500
3 months
Nationwide
⚖️

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteo…

Novo Nordisk A/S

The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and knee osteoarthritis. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.

Phase 3
Weight Loss
in-person
$500–$2,500
3 months
Nationwide
⚖️

Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function

University of Colorado, Boulder

Changes in adipose tissue biology are now recognized as a key factor underlying the increased risk of metabolic and cardiovascular disease with obesity. Clinical interest in adipocyte-derived extracellular vesicles (Ad-EVs) has intensified due to their potential as circulating biomarkers of adipose tissue health and systemic messengers, regulators and mediators of cardiometabolic health and disease with obesity. The investigators hypothesize that elevated Ad-EVs in adults with obesity will be…

Observational
Weight Loss
in-person
$500–$2,500
3 months
Colorado
⚖️

Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

Kailera

The primary objective of this study is to demonstrate that KAI-9531 subcutaneous (SC) injection once weekly is superior to placebo on: * Percent change in body weight * Change in hemoglobin A1c (HbA1c)

Phase 3
Weight Loss
in-person
$500–$2,500
3 months
Nationwide
💉

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Ty…

Hoffmann-La Roche

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA), at multiple doses compared with placebo for weight management in participants with obesity or overweight and Type 2 diabetes mellitus (T2DM).

Phase 3
Diabetes
in-person
$500–$2,500
3 months
Nationwide
💉

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Withou…

Hoffmann-La Roche

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA), at multiple doses compared with placebo for weight management in participants without Type 2 diabetes mellitus (T2DM) who have obesity or overweight with at least one weight-related comorbidity.

Phase 3
Diabetes
in-person
$500–$2,500
3 months
Nationwide
💉

A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants A…

AstraZeneca

The purpose of this study is to assess the pharmacokinetics (PK), safety and tolerability of different oral formulations of AZD5004, and to evaluate the effect of food on these formulations in healthy participants.

Phase 1
Diabetes
in-person
$500–$2,500
3 months
California
🧠

ALTO-207 in Adults With Treatment-resistant Depression (TRD)

Alto Neuroscience

The purpose of this trial is to measure depressive symptoms following treatment with ALTO-207 compared with placebo in participants with TRD.

Phase 2
Mental Health
in-person
$500–$2,500
3 months
Nationwide
🧠

Effect of Tao Calligraphy Meditation and Energized Water on Depression

Sha Research Foundation

The goal of this controlled randomized clinical study is to learn if a Tao Calligraphy Mindfulness and Energized water Practice works to improve Unipolar Depression. The main questions it aims to answer are: * Does Tao Calligraphy Mindfulness practice and drinking Energized water improve the subjective symptoms of Unipolar Depression in adults? * Does Tao Calligraphy Mindfulness practice and drinking Energized water improve the clinical symptoms and signs of Unipolar Depression in adults? * W…

Observational
Mental Health
in-person
$500–$2,500
3 months
Hawaii
🧠

Stress and Pain in People Living With HIV

Yale University

This is a basic human experimental study utilizing 4 groups of individuals with and without HIV and complex morbidities of cannabis use disorder and major depression who will participate in 2 sessions of the Yale Pain Stress Task (YPST) and follow-up phase to assess drug use and mood symptoms.

Observational
Mental Health
in-person
$500–$2,500
3 months
Connecticut
🫁

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

GlaxoSmithKline

Asthma is a chronic condition marked by narrowed and swollen airways due to inflammation leading to recurring symptoms that can vary and worsen unpredictably.\\xa0The purpose of this study is to assess how depemokimab, a monoclonal antibody, affects the structure and function of the lungs in asthmatic participants with type 2 inflammation, characterized by an eosinophilic phenotype.

Phase 3
Respiratory
in-person
$500–$2,500
3 months
Nationwide
🧴

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Du…

AbbVie

Atopic dermatitis (AD) is a skin condition that may cause a rash and itching due to inflammation of the skin. Therapies spread over the skin may not be enough to control the AD in trial participants who require systemic anti-inflammatory treatment. This study aims to provide data on the efficacy and safety of upadacitinib at different doses in adult participants with moderate to severe AD. Upadacitinib is an approved drug for the treatment of moderate to severe atopic dermatitis (AD). This st…

Phase 3
Dermatology
in-person
$500–$2,500
3 months
Nationwide
🧴

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or At…

National Institute of Allergy and Infectious Diseases (NIAID)

Background: Autosomal dominant hyper-IgE syndrome (HIES), also called Job syndrome, is a genetic disorder that affects the immune system. It can cause skin and lung infections and problems with blood vessels, connective tissues, and bones. People with HIES often have lupus-like disease or atopic dermatitis (skin rash). Researchers want to know if a drug approved to treat other immune system diseases (baricitinib) can help people with HIES. Objective: To test baricitinib in people with HIES wi…

Phase 1
Dermatology
in-person
$500–$2,500
3 months
Maryland
🧴

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Northwestern University

Single center, prospective, Open label study of sleep, pruritus and circadian function pre/post 12-weeks of dupilumab treatment in children 6-17 years old

Phase 4
Dermatology
in-person
$500–$2,500
3 months
Illinois
🛡️

A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults

ModernaTX, Inc.

The purpose of this study is to evaluate humoral immunogenicity after 2 doses of mRNA-1018-H5, and to evaluate the safety and reactogenicity of mRNA-1018-H5 in adults ≥18 years of age.

Phase 3
Vaccine
in-person
$500–$2,500
3 months
Nationwide
🛡️

A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults

GlaxoSmithKline

This early-stage study will look at a new mRNA vaccine that combines defenses against both seasonal flu and COVID-19 in terms of its safety and how it builds protection. Healthy adults aged 65 to 85 will receive different doses of this new vaccine, a standard flu vaccine, or COVID-19 vaccine. The study will assess any side effects or health issues, and additional blood samples will be collected at specific times to evaluate how well participants bodies build protection against the flu and COV…

Phase 1
Vaccine
in-person
$500–$2,500
3 months
California
🛡️

Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and Without ALFQ Adjuvant in Healthy Adults

National Institute of Allergy and Infectious Diseases (NIAID)

Background: Influenza (flu) is a contagious respiratory illness caused by viruses. Flu symptoms can range from mild to severe, and the illness can be fatal. Vaccines help the body learn to prevent or fight infections such as flu. Some vaccines are combined with adjuvants. Adjuvants are special salts or fats that help vaccines work better. Researchers are looking for ways to make flu vaccines more effective. Objective: To test a new flu vaccine with and without a new adjuvant. Eligibility: Hea…

Phase 1
Vaccine
in-person
$500–$2,500
3 months
Maryland
❤️

Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)

Regeneron Pharmaceuticals

This study is researching an experimental drug called REGN13335. The study is focused on participants with Pulmonary Arterial Hypertension (PAH). The aim of the study is to see how safe and effective REGN13335 is in participants with PAH who are taking other PAH medicines. The study is looking at several other research questions, including: * What side effects may happen from taking REGN13335 * How much REGN13335 is in the blood at different times * Whether the body makes antibodies against R…

Phase 2
Cardiology
in-person
$500–$2,500
3 months
Colorado
❤️

Study of Intravenous ZMA001 in Healthy Subjects

National Heart, Lung, and Blood Institute (NHLBI)

Background: A number of diseases can cause a type of lung injury called pulmonary arterial hypertension (PAH). Most people who develop PAH do not survive more than a few years. A new study drug (ZMA001) may help. ZMA001 is a monoclonal antibody. This type of drug consists of proteins, made in a facility, that are very similar to proteins in a human body. But before giving ZMA001 to people sick with PAH, researchers want to find out how the drug affects healthy people. Objective: To test a dru…

Phase 1
Cardiology
in-person
$500–$2,500
3 months
Maryland
❤️

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Mayo Clinic

The researchers are testing a medication named ravulizumab for the treatment of severe preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelets (HELLP) syndrome.

Phase 2
Cardiology
in-person
$500–$2,500
3 months
Minnesota
🦴

A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)

Amgen

The primary objective of this study is to evaluate the long-term safety and tolerability of dazodalibep.

Phase 3
Pain Management
in-person
$500–$2,500
3 months
Nationwide
🦴

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants…

AstraZeneca

The purpose of this study is to measure the safety, tolerability, PK, and PD of AZD5492 administered subcutaneously in adult participants with SLE or IIM or RA Study details include: • The study duration will be a minimum of 180 days in addition to the screening period. Additional follow-up visits may be required up to 12 months from study start. * Depending on the study part they are assigned to, participants will be administered AZD5492 once (Part 1) or twice (Part 2). * Study visits will o…

Phase 1
Pain Management
in-person
$500–$2,500
3 months
Nationwide
🦴

A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)

Merck Sharp & Dohme LLC

Researchers are looking for new ways to treat rheumatoid arthritis (RA). Methotrexate (MTX) is a standard (usual) treatment for RA. However, MTX and other current treatments may not work well to treat RA symptoms for many people. This study will help find out if a study medicine called tulisokibart can treat symptoms of active RA in people who are taking MTX. In this study, researchers will look at different doses of tulisokibart. Researchers want to learn if at least one of the study doses o…

Phase 2
Pain Management
in-person
$500–$2,500
3 months
Nationwide
🦴

A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

Eli Lilly and Company

The purpose of this study is to evaluate how well LY4213663 is tolerated and what side effects may occur in healthy participants and participants with rheumatoid arthritis (RA). The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body. The study will last approximately 33 weeks excluding screening.

Phase 1
Pain Management
in-person
$500–$2,500
3 months
Multi-State
😴

Light Exposure, Migraine Outcomes, and Sleep Quality

Arizona State University

The purpose of this study is to examine the relationship between daily light exposure patterns, sleep quality, and migraine characteristics in adults with migraine, with and without photophobia, across an 8-week study period.

Observational
Sleep
in-person
$500–$2,500
3 months
Arizona
😴

BfedBwell INSPIRE Pilot

University of Colorado, Denver

This single-arm pilot study will evaluate the feasibility and acceptability of a comprehensive survivorship lifestyle intervention addressing nutrition, exercise, sleep health, and stress management. The intervention integrates the BfedBwell survivorship nutrition program with the BfitBwell clinical exercise oncology program. The augmented BfedBwell program includes: (1) a core education curriculum, (2) 1:1 counseling with a registered dietitian, (3) behavioral skills development, (4) group s…

Observational
Sleep
in-person
$500–$2,500
3 months
Colorado
😴

Effect of Ashwagandha Root Extract on Stress, Anxiety, and Sleep Quality in Adults Experiencing Minority Stress

SF Research Institute, Inc.

Sexual and gender minority adults often experience elevated levels of chronic stress due to stigma, discrimination, and social adversity, commonly referred to as minority stress. This persistent stress is associated with increased anxiety, mood disturbances, impaired sleep quality, and reduced quality of life. There is a need for safe, non-pharmacological interventions that can support mental well-being in this population. This randomized, double-blind, placebo-controlled study is designed to…

Observational
Sleep
in-person
$500–$2,500
3 months
California
😴

PrP-targeting siRNA Safety & Mechanism Study

Broad Institute of MIT and Harvard

The purpose of this trial is to evaluate safety, tolerability, pharmacokinetics and pharmacodynamic impact of PrP-siRNA in symptomatic prion disease patients.

Phase 1
Sleep
in-person
$500–$2,500
3 months
Multi-State
🫁

A Study to Investigate How Budesonide and Formoterol Move Through the Body (Pharmacokinetics) When Delivered With Dif…

AstraZeneca

The purpose of this study is to assess the pharmacokinetics (PK) and safety of symbicort aerosphere and symbicort pressurized metered dose inhaler (pMDI) in participants with asthma aged 4 to less than 12 years.

Phase 1
Respiratory
in-person
$500–$2,500
3 months
Multi-State
🫁

A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compare…

AstraZeneca

The purpose of this study is to evaluate the effect of 2 different GP metered dose inhaler (MDI) doses relative to placebo MDI as add-on treatment to BFF MDI on lung function in participants 4 to less than 12 years of age with asthma.

Phase 2
Respiratory
in-person
$500–$2,500
3 months
Nationwide
🫁

Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison t…

Regeneron Pharmaceuticals

This study is researching a drug called dupilumab. The study is focused on patients who have uncontrolled asthma. Asthma is a condition where the airways narrow and swell, making it difficult to breathe. Uncontrolled asthma means that patients are still having frequent symptoms while taking their current asthma medication. The aim of the study is to see which regimen is more effective: taking dupilumab with an inhaled asthma medication or only taking a higher dose of the inhaled asthma medica…

Phase 4
Respiratory
in-person
$500–$2,500
3 months
Nationwide
🫃

Psyllium in Pediatric IBS

Dr Bruno Chumpitazi, M.D.

The goal of this clinical trial is to learn if a fiber (psyllium) can change the way bacteria use fructans (a type of sugar) and whether psyllium can help decrease childhood irritable bowel syndrome (IBS) symptoms when eating fructans. The main questions it aims to answer are: Aim 1: The effect of psyllium at two doses given with a fructan meal on microbial fructan fermentation (intracolonic pH; H2 gas production; gut microbiome composition; fecal short-chain fatty acids, lactate, glycomics).…

Phase 2
Gastrointestinal
in-person
$500–$2,500
3 months
North Carolina
🫃

Well-being in IBS: Strengths and Happiness (WISH) 2.0

Massachusetts General Hospital

The purpose of this study is to examine the feasibility, acceptability, preliminary effects, and candidate gut-brain mechanisms of an optimized positive psychology (PP) intervention for patients with irritable bowel syndrome (IBS), entitled "WISH," compared to an educational control intervention.

Observational
Gastrointestinal
in-person
$500–$2,500
3 months
Massachusetts
🫃

Efficacy of Rifaximin With NAC in IBS-D

Mark Pimentel, MD

The purpose of this study is to examine the effectiveness of using a combination of a drug, rifaximin and a dietary supplement, N-acetyl-L-cysteine (NAC), to treat patients with irritable bowel syndrome with diarrhea (IBS-D). Rifaximin is one of the standard treatments for IBS-D and is FDA approved. While rifaximin is safe and effective for treating symptoms in patients with IBS-D, many patients find that their symptoms may not completely resolve, or may come back after a period of time. This…

Phase 2
Gastrointestinal
in-person
$500–$2,500
3 months
California
🫃

A Prospective Trial of a Variable Compression System for Moderate to Severe Irritable Bowel Syndrome

PGP Health

This prospective, interventional trial is intended to determine the safety and effectiveness of the Variable Compression System (VCS) device for Irritable Bowel Syndrome (IBS). This pilot study will enroll 20 subjects who will be required to wear the VCS device for a minimum of 6 hours a day and follow up at 21 days, 8 weeks, and 6 months post-device administration.

Observational
Gastrointestinal
in-person
$500–$2,500
3 months
Multi-State
🌸

Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.

Granata Bio Corporation

The goal of this multicenter, randomized, placebo-controlled, double-blind clinical trial is toto evaluate the efficacy and safety of a human menopausal gonadotropin (hMG) in the development of multiple follicles, pregnancy, and cumulative live birth as part of an Assisted Reproductive Technology (ART) cycle in in women with a diagnosis of infertility.

Phase 3
Women's Health
in-person
$500–$2,500
3 months
Nationwide
🌸

Radicle Revive™: A Study Assessing the Impact of Health and Wellness Products on Menopausal-Related Health Issues Ass…

Radicle Science

Radicle Revive™: A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on menopausal-related health issues associated health outcomes.

Observational
Women's Health
in-person
$500–$2,500
3 months
California
🌸

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Deve…

National Cancer Institute (NCI)

This phase IIA trial compares the effect of acolbifene versus low dose tamoxifen in preventing breast cancer in premenopausal women at high risk for developing breast cancer. The usual approach for patients at increased risk for breast cancer is to undergo yearly breast magnetic resonance imaging or ultrasound in addition to yearly mammogram. Premenopausal women at very high lifetime risk for breast cancer (greater than 50%) can consider preventive removal (mastectomy) of both breasts. Premen…

Phase 2
Women's Health
in-person
$500–$2,500
3 months
Multi-State
🌸

Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women

Nutrition 21, Inc.

The goal of this study is to better understand how an amylopectin chromium blend may influence whole body protein balance in women during midlife, when hormonal changes can adversely affect protein metabolism and muscle maintenance. Continuous glucose monitoring will also be used to assess glycemic control over a 24-hour period. The main questions the study aims to answer are: * Does the use of an amylopectin chromium blend in peri- and post-menopausal women help to support positive protein b…

Observational
Women's Health
in-person
$500–$2,500
3 months
Ohio
💪

Effect of Text Message Reminders on M-ISI Score After Prostate Surgery

University of Rochester

The purpose of this study is to compare post-prostatectomy incontinence via Michigan Incontinence Score Index in patients receiving daily text message reminders for pelvic floor exercises when compared to those not receiving text reminders.

Observational
Men's Health
in-person
$500–$2,500
3 months
New York
💪

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Axonics, Inc.

To assess the post-market clinical outcomes of the Axonics SNM System for treatment of overactive bladder in male patients.

Observational
Men's Health
in-person
$500–$2,500
3 months
Nationwide
💪

Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate Cancer

National Cancer Institute (NCI)

Background: Men who are treated for prostate cancer often develop urinary leakage (incontinence). An experimental device that uses electrical impulses to stimulate pelvic floor muscles and surrounding tissues may help. Objective: To see if the Elidah device can reduce urinary incontinence after prostate treatment. Eligibility: Men aged 18 years and older who have had moderate urinary incontinence for at least 6 months after treatment for prostate cancer. Design: Participants will be in the st…

Phase 2
Men's Health
in-person
$500–$2,500
3 months
Maryland
💪

Ambulatory Long Length URodynamics Evaluation

Bright Uro

A prospective, open-label, single arm interventional trial evaluating the safety and performance of the in-clinic and extended monitoring of the lower urinary tract using the Glean Urodynamics System.

Observational
Men's Health
in-person
$500–$2,500
3 months
Multi-State
🎗️

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

Novartis Pharmaceuticals

The purpose of this open-label, multicenter, phase IIIb, single-arm study is to characterize the efficacy and safety of the combination of ribociclib and standard adjuvant endocrine therapy (ET) on invasive breast cancer-free survival (iBCFS), in a close to clinical practice patient population with HR-positive (HR+), HER2-negative (HER2-), Anatomic Stage Group III, IIB, and a subset of Stage IIA Early Breast Cancer (EBC).

Phase 3
Oncology
in-person
$500–$2,500
3 months
Nationwide
🎗️

A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

Hoffmann-La Roche

This study will evaluate the safety and efficacy of inavolisib combination therapies in participants with untreated, PIK3CA-mutated, Stage II-III, estrogen receptor (ER)-positive, Human Epidermal Growth Factor Receptor 2 (HER2)-negative breast cancer (BC).

Phase 2
Oncology
in-person
$500–$2,500
3 months
Nationwide
🎗️

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and Other Advanced S…

Novartis Pharmaceuticals

Phase I: Characterize safety and tolerability of ECI830 as a single agent and in combination with ribociclib and fulvestrant. Identify dose range for optimization/recommended dose for future studies. Phase II: Assess the anti-tumor activity of ECI830 in combination with ribociclib and fulvestrant in patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer.

Phase 1
Oncology
in-person
$500–$2,500
3 months
Nationwide
🎗️

Circulating Tumor DNA

Yale University

This is a single-arm, phase II study examining elacestrant in the adjuvant treatment of patients with ER+ breast cancer who test positive for circulating tumor DNA (ctDNA) during the screening period of the trial. Our trial will proceed in three separate phases: screening, treatment, and follow-up.

Phase 2
Oncology
in-person
$500–$2,500
3 months
Multi-State
🧬

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With…

Bristol-Myers Squibb

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC in adult participants with agitation related to Alzheimer's Disease.

Phase 3
Neurology
in-person
$500–$2,500
3 months
Nationwide
🧬

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With…

Bristol-Myers Squibb

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC in adult participants with agitation related to Alzheimer's Disease.

Phase 3
Neurology
in-person
$500–$2,500
3 months
Nationwide
🧬

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

Bristol-Myers Squibb

The purpose of this study is to evaluate the long-term efficacy and safety of combined formulation of xanomeline tartrate/trospium chloride in an immediate release (IR) capsule (KarXT) and xanomeline enteric capsules (KarX-EC) in participants with agitation associated with Alzheimer's Disease who completed the parent studies CN012-0023 or CN012-0024.

Phase 3
Neurology
in-person
$500–$2,500
3 months
Nationwide
🧬

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's D…

Bristol-Myers Squibb

The purpose of this study is to evaluate KarXT + KarX-EC as a treatment for psychosis associated with Alzheimer's disease.

Phase 3
Neurology
in-person
$500–$2,500
3 months
Nationwide
🩸

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

Merck Sharp & Dohme LLC

Researchers designed a study medicine called enlicitide to lower low-density lipoprotein cholesterol (LDL-C). In this study, researchers want to learn about giving enlicitide with another medicine called rosuvastatin. Rosuvastatin is a standard (usual) treatment to lower LDL-C. The goal of this study is to learn if enlicitide given with rosuvastatin works better than placebo on lowering LDL-C in a person's blood. A placebo looks like the study medicine but has no study medicine in it. Using a…

Phase 3
Cholesterol
in-person
$500–$2,500
3 months
Nationwide
🩸

A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of AZD4954 and Vice Versa in Healthy Adults

AstraZeneca

The purpose this study is to measure the impact of laroprovstat (AZD0780) on the pharmacokinetics (PK) of AZD4954 and the impact of AZD4954 on the PK of laroprovstat in healthy male and female participants.

Phase 1
Cholesterol
in-person
$500–$2,500
3 months
California
🩸

A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia

Eli Lilly and Company

The purpose of this study is to evaluate the safety and efficacy of solbinsiran in lowering triglycerides and other lipid measures compared to placebo in participants with severe hypertriglyceridemia. Participants will receive two subcutaneous injections.

Phase 2
Cholesterol
in-person
$500–$2,500
3 months
Nationwide
🩸

A Phase I Study Comparing the Relative Bioavailability of a Fixed-Dose Combination of Laroprovstat/Rosuvastatin vs Th…

AstraZeneca

The purpose of this study is to assess how well laroprovstat and rosuvastatin combined in a single tablet to be taken by mouth works compared with laroprovstat and rosuvastatin individual tablets taken by mouth (relative bioavailability) in healthy adults.

Phase 1
Cholesterol
in-person
$500–$2,500
3 months
California